In the normal "Hard Labours of an Assassin" side quest, you're sent to kill an unidentified man from Italy who is to be found somewhere in Sao Jorge. You talk to the tavern keeper who tells you the man is Vito Leone and he's waiting for you in the church. In "A Worm in the Apple", Vito has moved to Point au Pitre, Guadeloupe. The tavern keeper has nothing to say on the matter. Fortunately, having done "Hard Labours of an Assassin" in the past, I had an idea of where to look, so I was able to complete the quest anyway.